Endocrine Abstracts

Introduction: Immune checkpoint inhibitors targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), programmed cell death ligand 1, and its ligand (PD-1/PD-L1) have become the current standard of care for many cancers. The mechanism of action of these drugs results in some new types of adverse events related to the immune system, most frequently involving the pituitary and thyroid glands.Case report: We present a case of mixed hypothyroidism (prim...

Introduction: Primary adrenal lymphoma is a rare cause of adrenal insufficiency, with most cases being of B-cell lymphoma.Case report: We present the case of a 51 yo man with a 1.5-month history of recurrent fever, nausea, vomiting, anorexia, weight loss of 12 kg, fatigue, polyarthalgia, hypotensive episodes (70/40 mmHg) and singultus. Before admission in our clinic he had a thoracic CT scan, which showed a 5.5 cm right adrenal mass and hyperplasia of th...